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In its active, "reduced" state, it acts as a primary internal defence mechanism
However, further research is needed to fully understand its long-term impact on MASLD/MASH progression and outcomes across diverse patient populations
The rates of pre-existing atrial fibrillation and heart failure were 12.5% and 33.4%, respectively
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Most patients start at a low dose and titrate upward over several weeks under physician guidance
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