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Site rotation best practices: Alternate between left and right thighs with each injection Move the injection site within the thigh area systematically (e.g., clockwise pattern) Avoid injecting into areas with scars, moles, or lesions Do not inject into areas with visible lipohypertrophy or lipoatrophy Regularly inspect injection sites for changes in skin texture or appearance The angle of injection is equally important for proper technique
[15] A recent study on melasma patients noted significantly higher levels of glutathione-peroxidase enzyme in patients compared to controls, confirming the role of oxidative stress in melasma
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doi:10.1136/ebmental-2019-300096 Rith-Najarian LR, Mesri B, Park AL, Sun M, Chavira DA, Chorpita BF
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