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NbGSTU4 binds to the 3 untranslated region (UTR) of BaMV positive sense (+) RNA in a GSH-dependent manner and is necessary for efficient viral RNA replication i.e., production of a viral negative sense () RNA and then new genomic (+) RNA (Chen et al., in vivo BaMV replication and in vitro () RNA synthesis, while oxidative agents inhibit in vitro () RNA synthesis (Chen et al., Resistance-Inducing Symbiotic Microorganisms and Plant GSTs Non-pathogenic, symbiotic bacteria and fungi living in the rhizosphere of plants can be highly beneficial to plants attacked by pathogenic microorganisms

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Long-lasting effects One injection lasts 4-6 weeks, so patients only need injections every month or two for maintenance

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This reduction leads to decreased cystine levels in the cancer cells, subsequently causing insufficient GSH synthesis and a decline in GPX4 activity