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Association between different GLP-1 receptor agonists and gastrointestinal adverse reactions:a real-world disproportionality study based on FDA adverse event reporting system database

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LIRA and SEMA gained approval from the Food and Drug Administration and the European Medicines Agency for weight loss in obese individuals or people who are overweight with BMI 27 kg/m 2 and have experienced at least one weight-associated comorbid condition (such as prediabetes, hypertension, dyslipidaemia, and OSA) combined with lifestyle modifications [63]