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Similar caution applies to more recent short-term combination studies reporting improvements in ovulation, endocrine markers, or related reproductive parameters, because endpoint definitions, denominators, concomitant therapies, and follow-up windows varied across trials (103, 104)
Women taking semaglutide who are also on hormonal birth control or HRT face compounded risk factors
COVID-19 infection: The main analysis of the primary estimand will include participants with COVID-19 infection
