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Indeed, there is evidence that links elevated serum homocysteine levels with Alzheimer disease
In this review, however, underexplored peptidereceptor systems are defined not by limited biological knowledge, but by a persistent mismatch between biological validation and pharmacologic exploitation
In the context of GLP-1 therapy, lithium may reinforce downstream neurotrophic and anti-inflammatory signaling, potentially strengthening long-term synaptic maintenance and cognitive resilience