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Hydrolysis is the breaking of peptide bonds through reaction with water molecules, a process that accelerates significantly with rising temperature this is the primary reason reconstituted peptides must be refrigerated rather than left at room temperature

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Mechanistic rationale is a starting point, not a conclusion

Kumar P, Patel M, Oster RA, Yarlagadda V, Ambrosetti A, Assimos DG, Mitchell T (2021) Dietary oxalate loading impacts monocyte metabolism and inflammatory signaling in humans