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Patients initiating semaglutide often have multiple cardiovascular risk factors, including obesity, diabetes, hypertension, and metabolic syndromeall conditions independently associated with cardiac arrhythmias and palpitations

22,4042 The efficacy of GLP-1 RAs in depressive symptoms primarily derives from animal studies, making it challenging to draw definitive conclusions

Adrenergic and cholinergic agents, growth factors, inflammatory mediators, and other autocrine and endocrine stimuli also contribute to the regulation of the functional activity of melanocytes [6]

Martn Del Valle EM

The blog also explains its role in clinical trials