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The most common causes include B12 supplementation (particularly injections), liver disease releasing stored B12, haematological disorders increasing B12-binding proteins, and chronic kidney disease reducing B12 excretion
Trade-offs include less flexibility in dose adjustment and prolonged exposure if adverse effects develop
When filmmaker Laura Nixs elderly cat had an intestinal blockage, her vet suggested a B12 injection along with an enema
The cancelled Phase I trial that would have tested oral BPC-157 in 42 healthy volunteers never published results, leaving that data inaccessible
Plus, the body very quickly urinates any excess of B12
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