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These include changes in the size and pigmentation of moles, rapid appearance of new moles, flushing to the face, abdominal cramps, nausea, vomiting, chest pain and brain swelling

for example, the site of conjugation of the linker can affect the PK of the ADCs through effects on stability while the ADC is within circulation or after internalization and more unstable linkers may lead to a faster decline in antibody concentrations [20]

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Single-cell proteomic characterization of drug-resistant prostate cancer cells reveals molecular signatures associated with morphological changes

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