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Wilcox, T.P
McGraw-Hill / Lange rxlist.com (Onglyza ) Keywords Linagliptin Trade Name: Tragenta Drug Class: oral hypoglycemics Mechanism of Action: An inhibitor of dipeptidyl peptidase-4 (DPP-4), a protease that degrades the incretin GLP-1 Pharmacokinetics: biliary tract excretion - unique elimination route amongst the DPP-4 inhibitors useful for Type II diabetic patients with reduced renal function
Interestingly, after discontinuation, the Harmony Outcomes trial (2018) reported that albiglutide did significantly reduce cardiovascular events by ~22% versus placebo ( [8] )
Ipamorelin a selective ghrelin receptor agonist emerged from studies in the 1990s investigating ghrelin mimetics and their ability to stimulate growth hormone release with minimal off-target hormonal effects
Resources We Trust Cleveland Clinic: Weight Loss Medications Mayo Clinic: Considering GLP-1 Medications
