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doi: 10.2165/00007256-200434080-00003 68 Skrzypiec-SpringMRozmusJAbu FarajGMielczarekMSroczynskaPSroczynskiJet al
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doi: 10.3390/clinpract13040070 47
3 But aging, stress, and daily environmental exposures drain antioxidant capacity
Thus, although negative selection against VAMP1 reduces cleavage on SNARE targets, evolution on procaspase-1 appears to confer caspase-like substrate preferences that include IL-1 or substrates with complete homology to the P2P4 of procaspase-1 such as ORC1 (residues 691707)
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