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Use this storage checklist to maintain semaglutide integrity: (1) keep all unopened doses refrigerated in a dedicated, clearly labeled section

In practice, this involves giving an initial 4 g IV infusion of pyridoxine, followed by repeated 1 g IM injections every 30 minutes until the total matched dose is reached

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NOXs are a family of membrane-bound enzymes expressed in epidermal keratinocytes and skin fibroblasts