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J Clin Endocrinol Metab (2004) 89(6):305561

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For others, it reduces the general reward response, making things that used to feel rewarding feel duller, which can appear as low mood or lack of interest

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The pronounced dependence of persistent, drug-resistant malignancies on GPX4 underscores its importance, and its inactivation has the potential to eliminate these cancer cells in vitro and avert tumor recurrence in vivo [216]

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