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Description

Serious adverse events have not been widely reported, but this may reflect the relatively small number of people who have used the compound and the limited reporting mechanisms available

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In diet-induced obese models, it produced a 7-10% reduction in body weight in just 11 days by increasing the basal metabolic rate

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In rodent studies, NNMT inhibition was associated with shifts in metabolic substrate utilisation

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NNMT inhibition combined with exercise enhances skeletal muscle endurance and grip strength in aged mice

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