Not only does LC supplementation improve reproductive parameters in PCOS patients, but it can also confer positive effects on other health parameters in these women
Overall, while GLP-1RAs may offer metabolic benefits in PCOS management, the increased risk of nausea and dizziness should be carefully considered in clinical practice 33
Central nervous system involvement is further supported by GLP-1 production in caudal brainstem neurons, key integrators of vagus nerve-mediated gut-brain signaling 53,54,55,56
Stanford suggests considering the following alternatives: Phentermine/topiramate ER (which has stronger efficacy and is FDAapproved for long-term use) GLP1 receptor agonists (e.g., semaglutide) Dual GLP1/GIP agonists (e.g., tirzepatide) Naltrexone/bupropion Orlistat in select cases The bottom line on phentermine for weight loss Phentermine can be an effective, affordable option for jump-starting weight loss, especially if you need short-term appetite support and pair it with a healthy diet and exercise
Challenges : Regulatory scrutiny in EU and US markets requiring full traceability and safety documentation