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found that intrathecal exenatide effectively and reversibly blocked bone cancer-induced mechanical allodynia in ipsilateral paws, with the peak effect at 0.5 h and a duration longer than 4 h in rat models of bone cancer pain [24]
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Although much of the research has focused on larger peptides and growth factors [25, 26], smaller peptides, particularly tripeptides composed of only three amino acids, are now gaining attention for their efficiency
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