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Semaglutide is a glucagon-like peptide-1 (GLP-1) receptor agonist formulated as a protein-based medication that requires gentle handling

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Normally glucagon is known for increasing blood glucose, but when carefully balanced alongside GLP-1 and GIP stimulation it may also: increase energy expenditure stimulate fat metabolism increase calorie burning improve liver fat reduction promote greater weight loss Essentially, GLP-1 and GIP reduce calorie intake whilst glucagon may increase calorie expenditure