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eLife 9:e57028
MAKUTINA, V., ISAEVA, A., KRIVONOGOVA, A
The depletion of GPX4 and GSH, the increased level of lipid peroxidation, and disrupted iron metabolism are vital features of ferroptosis ( Being a novel mode of cell death, ferroptosis is known to be related to tumor progression and therapeutic efficacy
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Notably, while excess iodine is well known to trigger thyroid autoimmunity in susceptible individuals, evidence from the literature is reassuring that an adequate iodine status (defined as a UIC between 100 g/L and 299 g/L) is safe in this regard [25, 26]
