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M.Brown-FrandsenK.ColhounH
The Phase II detoxification pathway, in which glutathione plays the central role, represents the critical step that converts potentially harmful substances into water-soluble compounds suitable for elimination
Data Availability All model parameters and kinetic information are presented in the supplementary information
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The ENGOT-ov65/KEYNOTE-B96 Phase III study demonstrated that checkpoint inhibitor pembrolizumab combined with weekly paclitaxel with or without bevacizumab, an anti-angiogenic monoclonal antibody, achieved a statistically significant overall survival benefit over weekly chemotherapy with/without bevacizumab
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