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If Im treating a diabetic patient on metformin who wants to try semaglutide, I usually add it and continue metformin until I see how their glucose levels respond, says Jennifer Brown, DO, ABOM, ABFM, a board-certified obesity and family medicine specialist at Maxwelton Health Center in West Virginia

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Gastrointestinal Issues (Most Common) Nausea Vomiting Diarrhea Constipation Abdominal pain Bloating Excess gas Heartburn Fatigue 2