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A p-value less than 0.05 was considered statistically significant
Ipamorelin and GH Secretagogue Selectivity Research Ipamorelin was identified as the first GHRP-receptor agonist with a selectivity for GH release comparable to that of GHRH itself, making it a highly valuable research tool for studying the GH axis without unwanted hormonal interference
Notably, the primary Phase 2 obesity trial enrolled participants largely without type 2 diabetes, so effects in people with diabetes may differ
Direct contact between the peptide and esophageal tissue during swallowing provides local exposure in addition to systemic effects achieved after absorption
The 2024 Standards of Care in Diabetes does emphasize use of certain GLP-1 medications over others for certain goals
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