glp-1 oral meds Wegovy Pill Becomes First Weight-Loss Drug Approved in U.S A GLP-1 Pill May Help

It does that through two main mechanisms

3.4.5 TFEB Transcription factor EB (TFEB) belongs to the MiT/TFE family of basic helix-loop-helix leucine zipper transcription factors and serves as a pivotal regulator of autophagy and lysosomal biogenesis (246)

This dimerization appears to induce a switch in intracellular signaling cascades in which administration of a dopamine agonist (quinpirole) alone leads to a rapid increase in Ca 2+ levels, an effect not observed in preparations expressing D2R in the absence of GHSR1a (Kern et al., 2012)

So it basically gives you cravings

His stack has been consistent across multiple episodes