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Analysis of the promoter regions of SLC7A11 and SLC3A2 utilizing the online resource JASPAR ( revealed the presence of potential estrogen response element (EREs), resembling the ER binding motif, situated within the 1.5 kb promoter regions upstream of the transcription start sites of SLC7A11 and SLC3A2 (Fig
In practice, TB-500 remains outside FDA-sanctioned compounding and is sold only as an unregulated research chemical
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The animal study was conducted in adherence to the Animal Research: Reporting of In Vivo Experiments guidelines, and all experimental procedures were approved by the Local Animal Ethics Committee of Gazi University (approval number: G..ET-19.057
doi: 10.2903/j.efsa.2021.6769, 221
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