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Lack of historical evidence to support folic acid exacerbation of the neuropathy caused by vitamin B12 deficiency

This compares solvent suitability for research, not human hydration

Before we dive into the particulars of this treatment, its important to understand what exactly this treatment entails

Gastrointestinal symptoms (more common with oral preparations): Mild nausea or upset stomach Diarrhoea (typically with very high doses) Other effects: Headache, particularly when treatment is first initiated Dizziness or light-headedness Skin reactions such as mild rash or itching Temporary reddish discolouration of urine (chromaturia) after hydroxocobalamin injections, which is harmless It is important to note that many symptoms attributed to B12 supplementation may actually represent the body's response to correcting a deficiency

What the Phase 2 trial documented week 1 through month 6 at 0.5mg/day oral