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Nat Rev Cardiol 9:147157

doi: 10.1007/s13300-024-01674-8 Bouhajib M, Tayab Z, Di Marco C, Suh D

Does Obesity Affect the Severity of Exercise-Induced Muscle Injury

We observed a significant increase in the autophagy substrate sequestosome 1 (SQSTM1, best known as p62) levels in both 6- and 20-week-old Alms1 -/- mice, as compared to age-matched WT controls, suggesting a reduction in autophagic flux (Fig