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GLP-1 therapies have been established using two main approaches: DPP4-resistant GLP-1 agonists/GLP-1RA and DPP-4 inhibitors, both of which aim to prolong the life-time of circulating GLP-1(736) amide

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Solenos stock soared 40% after the FDA nod and has held fairly steady since, with the company valued at nearly $4 billion as of early June