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Unlike the other weight-loss agents which reduce appetite and/or enhance energy expenditure, orlistat inhibits pancreatic and gastric lipases, thereby reducing fat absorption from the gut

Speak to your GP if you experience: Severe or persistent abdominal pain, particularly in the upper right or upper middle abdomen Jaundice (yellowing of the skin or whites of the eyes) Persistent vomiting Dark urine or pale stools Fever alongside abdominal symptoms Persistent watery or urgent diarrhoea that doesnt settle after the first few weeks on a stable Mounjaro dose Heartburn or reflux is noticeably worse than before starting Mounjaro Some people experience increased bile reflux after gallbladder removal, and Mounjaros slowing of gastric emptying can make this worse

Your healthcare team should establish a monitoring schedule that includes assessment of both physical health markers (weight, blood glucose, blood pressure, lipid profile) and mental health indicators (mood stability, sleep quality, medication adherence)

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How can I manage common Mounjaro side effects