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Boosted Blood Volume: Tackle the issue of low plasma volume, often seen in POTS patients, which can intensify symptoms
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In our bulk RNAseq data, we noted that pathways such as oxidative phosphorylation and electron transport chain were significantly downregulated ( Supplementary Figures 5B, C )
It uses a methyl group donated by S-adenosylmethionine (SAM) to methylate nicotinamide a vitamin B3 form that would otherwise be recycled back into NAD+
Fourth, it is a strong anti-oxidant because it neutralizes oxidative stress markers such as malondialdehyde
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