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GLP-1 (glucagon-like peptide-1) is an endocrinal peptide hormone expressed by the pancreas and by many other organs including the gastrointestinal tract, the heart and the brain 25,26
Therefore, given the challenges posed by chemotherapy-induced EMT and the associated increase in invasiveness, the anti-migratory effects of chlorophyllin alongside GSTP1 inhibition could play a role in improving the outcomes of docetaxel therapy for metastatic TNBC
These effects help preserve kidney function and slow the progression of chronic kidney disease
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Quellen: Nauck, M
Kodali LSM et al
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