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Here is how it works: the enzyme carnitine palmitoyltransferase I (CPT-I) on the outer mitochondrial membrane converts fatty acyl-CoA to fatty acylcarnitine by attaching it to a carnitine molecule
doi: 10.1002/imt2.88 372 ZhangB.YangH.CaiG.NieQ.SunY
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This also helps to narrow down the diagnosis and exclude other conditions with similar symptoms
As shown in Figure 4A, cinchonine potentiated insulin secretion under high glucose conditions (11.1 and 16.7 mM) but had no effect under 2.8 mM glucose, which suggested that cinchonine induced insulin release in a glucose-dependent manner
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