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Suspected side effects from any medicine, including unlicensed compounds, should be reported to the MHRA via the Yellow Card scheme at yellowcard.mhra.gov.uk

It helps people feel fuller for longer, slows the rate at which carbs are broken down and prevents sugar from flooding the bloodstream

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Around the same time, I think you remember that all of pharma was interested in obesity in the early 90s, everyone wanted to do diabetes as well as obesity, but they were separate teams and they all wanted to do small molecules, but it just happens to be so that the best idea we could find at that time was actually GLP-1, because we actually had clinical data relatively early that GLP-1 was a really good candidate as a treatment for diabetes because of the glucose sensitivity of the actions

A phase 2 clinical trial published in JAMA (2023) reported significant reductions in body weight and improvements in metabolic markers