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Brozinick, J
The injectable medications mimic a hormone made in the gut called glucagon-like peptide-1 (GLP-1), which helps manage blood sugar, reduce appetite and slow stomach emptying so you feel fuller, longer
Methotrexate works by binding to the hydrofolic reductase enzyme, which hinders the conversion of folic acid to folinic acid and consequently affects the synthesis of certain amino acids and nucleic acids
GIP (glucose-dependent insulinotropic polypeptide) is another gut hormone that, like GLP-1, helps regulate blood sugar and appetite, so activating both pathways may provide additional benefits
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