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Unlike FDA-approved medications with standardized appearance, compounded formulations may show batch-to-batch color variations even from the same pharmacy
20% uncertainty applies to all estimates
Modulation of gamma-aminobutyric acid (GABA)related signaling has been observed in preclinical models, a mechanism that may contribute to reduced anxiety-like behaviors and enhanced neural stability (27)
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A 12-week randomized trial demonstrated: Average weight loss of 2.6 kg in AOD-9604 group (1 mg/day) versus 0.8 kg in placebo group Preferential reduction in abdominal and visceral fat deposits No adverse effects on carbohydrate metabolism or insulin sensitivity Non-dose-dependent effects, with higher doses (10 mg/day) producing less weight loss than lower doses However, a subsequent 24-week Phase III trial with 502 subjects incorporating intensive diet and exercise showed no statistically significant weight loss compared to placebo, leading to development termination in 2007
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