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For topical cosmetic use on intact skin , the answer from the available evidence is that systemic copper absorption is minimal
However, toxins such as environmental pollutants, drugs, and chemicals in food can impair the methylation pathway by interfering with the enzymes involved in the process and depleting the body's stores of crucial components like SAMe and methionine
But despite their frequent association they're combined in the GLOW Blend, KLOW Blend, and many research protocols they are fundamentally different compounds with distinct mechanisms, structures, and research applications
We recommend starting one compound first (typically the GLP-1 medication), stabilizing on that dose, and then adding the second compound