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Slower digestive pace can affect: Fullness and appetite : feeling satisfied faster Nausea : particularly when starting or increasing doses Constipation : from slower intestinal transit Diarrhoea : paradoxically, some people experience the opposite Bloating and abdominal discomfort : symptoms many IBS sufferers already know too well

Avoid large, fatty, or greasy meals that may worsen nausea

By adding B12, which supports red blood cell health and efficient fat metabolism, patients may experience more stamina, reduced fatigue, and better complianceall factors that reinforce long-term success

GLP-1 therapy partially overrides this response

The SELECT trial, found that those who received a weekly 2.4 mg dose of semaglutide had a 20% reduction in major adverse cardiovascular events