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Access this article Similar content being viewed by others Data Availability The datasets generated or analyzed for this study are available from reasonable requests to the corresponding author

While it is intuitively assumed that antioxidants emerged during the GOE to defend against O 2 reactivity and toxicity caused by the accelerated oxygenation of the atmosphere, sequencing and phylogenetic analyses of antioxidant systems from ancient organisms suggests that antioxidant enzymes including SODs may have originated long before the surge of atmospheric and oceanic O 2 (Wolfe-Simon et al

(NAC and Acetaminophen) Fisher ES, Curry SC

Insulin signalling and glucose transport in the ovary and ovarian function during the ovarian cycle