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Neuropsychopharmacology 35, 21432154
Include healthy fats : Incorporating moderate amounts of unsaturated fats from sources like olive oil, avocados, nuts, and fatty fish may support GLP-1 secretion, though evidence specifically comparing fat types is still emerging
To determine the specificity of Semaglutides actions, we used small interfering RNA (siRNA) to knock down the GLP-1 receptor (GLP-1R) in Ang II-stimulated cardiomyocytes
Dietary modifications that may support metabolic health include: Including a source of protein at each meal, as protein can stimulate GLP-1 release Including dietary fibre , particularly soluble fibre from vegetables, legumes, oats, and wholegrains, which may promote GLP-1 secretion through fermentation by gut bacteria Eating regular, balanced meals that align with the NHS Eatwell Guide recommendations Limiting ultra-processed foods high in refined carbohydrates and unhealthy fats Considering fermented foods such as yoghurt, kefir, and sauerkraut, which may benefit overall gut health, though direct effects on GLP-1 require further research Lifestyle factors that support metabolic health include: Regular physical activity , with both aerobic exercise and resistance training showing benefits for glucose metabolism
Fasting is not required and not recommended
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