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J Natl Cancer Inst 113(2):208-211, 2021

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Better protection of the active ingredient from degradation

Non-Small Cell Lung Cancer: Role of Surgical Resection in Multidisciplinary Treatment

For purine synthesis, 5-PRPP is converted into phosphoribosyl--amine (PRA) with the addition of an amide group from glutamine by phosphoribosyl pyrophosphate amidotransferase (PPAT)