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This work demonstrated that GLP-1RA treatment was associated with a significant 29% reduction in MALOs compared to non-use (IRR: 0.71, 95%CI: 0.57-0.88, P = 0.003) over a median follow-up of approximately 70,045 patient-years
TRIM46 contributes to high glucose-induced ferroptosis and cell growth inhibition in human retinal capillary endothelial cells by facilitating GPX4 ubiquitination
Regular use supports overall resilience against environmental and metabolic stressors
So instead of broadly suppressing calories, these compounds work with your biology
Anecdotal evidence and pharmacoepidemiological studies in humans report reduced alcohol use by patients using GLP-1RAs for other indications
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