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It is therefore unsurprising that the LD 50 values for compounds 1 and 2 determined ex vivo have a similar discordance to that seen for PZQ when considering in vivo PK/PD: much like PZQ these compounds are schistosomicidal in vivo at sub LD 50 concentrations
10.1088/1758-5090/ac36de 74 LeeY
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The result is a clear, colorless liquid without odor (or with a very faint characteristic odor of benzyl alcohol), ready to serve as a reliable solvent for sensitive peptide molecules
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