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[] This finding challenges previous results indicating marked differences in eryptosis between HD and PD patients, and it underscores the need for further studies on the factors influencing RBC survival in these populations

Abbasi SH, Heidari S, Mohammadi MR, Tabrizi M, Ghaleiha A, Akhondzadeh S

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Altogether, these examples underscore that despite encouraging experimental results, ferroptosis-targeted drugs face multiple translational bottlenecks, including systemic toxicity, insufficient targeting, metabolic compensation, and biological heterogeneity