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Gallbladder disease : Including cholelithiasis and cholecystitis, particularly in those experiencing substantial weight loss Renal impairment : Secondary to dehydration from gastrointestinal side effects Ileus/intestinal obstruction : Post-marketing reports exist with GLP-1 receptor agonists (causality not established)

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I frame GLP-1 therapy as an adjunct, not a replacement, for dermatologic systemic treatment

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