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Each component plays a distinct role: choline and methionine are involved in the transport and breakdown of fats in the liver, and inositol participates in cell signaling

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In addition, low IGF-1 subjects in a study were found to possess up-regulated fatty acid metabolism along with down-regulated GLUT-1 gene (in charge of glucose uptake in erythrocytes, brain endothelial cells, eye, peripheral nerve and also responsible for materno-placental glucose transfer) [210]