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A 2025 pilot study in surgical aortic valve replacement patients reported that cf-mtDNA increased ~16-fold during CPB and that those with higher mtDNA had more postoperative infection and longer hospital stays (170), demonstrating that preventing mitochondrial oxidative damage can reduce DAMPs release

The ones who struggle are often eating through the signal (usually palatable processed foods that don't trigger fullness the same way whole foods do)

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But I do get v tired and sleep more than average but my lifestyle is a lot less stressful now

K., Paal, M