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Its possible the associated loss of bone density could be due to patients eating less as well, he said
Why has your own GLP-1 stopped working
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However, DPP-4 inhibitors (such as sitagliptin or linagliptin) should be discontinued when initiating semaglutide, as both drug classes work through incretin pathways, and combined use offers no additional glycemic benefit while potentially increasing adverse effects
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