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Br J Pharmacol 174(10):933949 Halls ML et al (2015) International union of basic and clinical pharmacology

This information helps your healthcare team assess whether symptoms are improving, stable, or worsening, and guides management decisions

Here's the general pattern folks tend to experience

Because a major physiologic function of GSH is to provide cells with a reducing environment and to destroy the reactive oxygen compounds and free radicals formed in metabolism, organs that have low concentrations of other antioxidants (such as catalase and superoxide dismutase) are thought to be more dependent on GSH for detoxification of reactive oxygen species than are organs that have alternative antioxidants

So did a counselor, who suggested he might be depressed