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Orforglipron A promising oral non-peptide GLP-1RA showing: Significant HbA1c reduction Double-digit weight loss Improved convenience Potential global accessibility This may dramatically expand the use of GLP-1 therapy worldwide
Dihexa reversed learning and memory deficits at concentrations as low as 10^-13 M (picomolar range), approximately 10 million times more potent than BDNF on a molar basis for promoting synaptogenesis
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Individuals with a loss-of-function single nucleotide polymorphism (SNP) in the PEMT gene, such as the rs12325817 variant, have a drastically reduced ability to synthesize their own phosphatidylcholine internally
doi: 10.3389/fnut.2022.1007816 Received 31 July 2022 Accepted 12 October 2022 Published 01 November 2022 Volume 9 - 2022 Edited by Yannan Jin, De Montfort University, United Kingdom Reviewed by Mostafa Waly, Sultan Qaboos University, Oman
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