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Metformin increased postprandial GLP-1 secretion compared with placebo (P = 0.014), and the postprandial glucose excursions were significantly smaller after metformin + saline compared with metformin + Ex9-39 (P = 0.004)
Diabetologia 53 , S339 (2010)
Observational studies reporting vitamin D and micronutrient insufficiencies during prolonged GLP-1RA use [94, 95, 101] suggest that nutritional monitoring may be warranted, although the magnitude and causal pathways remain to be clarified
Some including zinc, iron, copper, and selenium are essential nutrients at trace levels
This weight-based dosing is designed to stimulate adequate growth in growing children
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