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doi:10.1016/bs.vh.2022.01.016
Surprisingly, this intestinal GLP-1 didn't work by boosting insulin secretion
However, despite the lack of statistical significance, the authors noted a consistent directional trend toward lower BMD in the semaglutide group at follow-up
In the SURMOUNT-1 Trial (a study on obesity), participants lost up to 24.2% of their body weight over 48 weeks the most significant weight reduction seen in an anti-obesity medication to date
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